Amanda Brambila

Research Lab: Doug Kellogg

Department: Molecular, Cell & Developmental Biology

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David Carrillo

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Ian Colinas

Research Lab: Scott Oliver 

Department: Chemistry and Biochemistry

Research Discription:

Synthesis and design of cationic metal-organic frameworks (MOFs) for the removal of oxo-anionic pollutants and antibacterial composite materials.

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Presentations:

IRMOF Thin Films Templated by Oriented Zinc Oxide Nanowires. Ian R. Colinas, Jesse Hauser, Scott RJ. Oliver, San Diego, ACS, 2012. Poster Presentaion.

IRMOF Thin Films Templated by Oriented Zinc Oxide Nanowires. Ian R. Colinas, Jesse Hauser, Scott RJ. Oliver. Seattle, WA. Society for Advancement of Chicanos/Hispanics and Native Americans in Science (SACNAS) Conference, 2013. Poster Presentation 

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Oscar Fernandez

Research Lab: Lindsay Hinck

Department: Molecular, Cell & Developmental Biology

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Kendy Hoang

Research Lab: Bin Chen

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The mammalian cerebral cortex is one of the most advanced and complex organs of the body that is responsible for our highest cognitive functions. The cortex consists of six distinct layers (VI-II/III) that form in an inside-out manner, where layer VI forms first and layers II/III form last. The neurons that occupy each layer differ in morphology, axon targets, and electrophysiology. Defects in the development of the neurons within these layers can lead to severe neurological disorders, such as intellectual disability. However, the mechanism of how these developmental defects that arise in the cortex remains unknown. I focus on investigating the role of Satb2, a transcription factor that is involved in cell-fate determination, neuronal migration, and soma spacing of cortical projection neurons. Understanding the molecular basis of how Satb2 regulates these different aspects of cortical development will lead to better understanding of neurological disorders that are associated with mutations in SATB2.

Publications:

McKenna WL, Ortiz-Londono CF, Mathew TK, Hoang K, Katzman S, Chen B. Mutual regulation between Satb2 and Fezf2 promotes subcerebral projection neuron identity in the developing cerebral cortex. Proceedings of the National Academy of Sciences. National Acad Sciences; 2015;112: 11702–11707. doi: 10.1073/pnas.1504144112.

Presentations:

Investigating Satb2's role in neuronal migration and soma spacing of cortical projection neurons. Kendy Hoang, University of California-Santa Cruz. Neuroscience Club, Santa Cruz, CA. 2017. Poster Presentation

Cloning of Enhancer 434 and Sox5 Enhancer into a Luciferase Reporter Vector. Kendy Hoang with Professor Bin Chen. University of California, Santa Cruz. Undergraduate Research Symposium. 2015. Poster Presentation

Cloning of SPT5 Fragment using Molecular Cloning Techniques. Kendy Hoang and Joanna Perez with Professor Grant Hartzog in the Summer Research Institute. University of California, Santa Cruz. 5th Physical and Biological Sciences Summer Research Symposium. Summer 2014. Poster Presentation.

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Oarteze Hunter

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Jorge Jimenez

Research Lab: Pradip Mascharak 

Department: Chemistry & Biochemistry

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Myresearch interests are on the design, synthesis, and characterization of photoactive carbon monoxide releasing molecules (photoCORMs) for the bioimaging and eradication of cancer cells. In addition, I have worked on the conjugation of luminescent rhenium derived photoCORMs within biocompatible natural polymers towards application in live-cell imaging and light induced CO delivery to malignant cells in a site specific manner.

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Synthesis, Structure and Assessment ofAntimicrobial Activities of Water Soluble SilverComplexes. Long Beach, CA. SACNAS National Conference. 2016. Poster Presentation

Light-triggered CO delivery to neoplastic target by a water-soluble and biocompatible manganese photo-CORM. Philadelphia, American Chemical Society National Conference. 2016. Poster Presentation

Synthesis and Assessment of CO-Release Capacity of Manganese Carbonyl Complexes Derived from Rigid a-Diimine-Ligands of Varied Complexity. Washington DC, SACNAS National Conference. 2015. Poster Presentation.

Awards:

Outstanding Oral Presentation at the 2016, SACNAS National Diversity. Long Beach, CA

SACNAS/ACS Chemistry Award Recipient Travel Scholarship forAmerican Chemical Society (ACS) Fall National Meeting, August 2016, Washington, DC

SACNAS Conference Travel Scholarship Award 2016


London Johnson

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Tannia Lau

Research Lab: Scott Lokey

Department: Chemistry & Biochemistry

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We are performing imaged based cytological profiling high-throughput screenings that allows you to screen drugs in a 384 well format. We use this approach to analyze cellular phenotypes (nuclei, cytoskeleton, microtubules, ER, Golgi, S-phase, and mitotic markers) induced by chemical compounds. We can compare these phenotypes to a mechanism of action reference library. Then quantify these features using a multivariate statistical analysis platform based on organelle intensity, size, shape, and absence/presence, etc... We aim to approach natural product drug discovery by classifying bioactive compounds based on their cytological fingerprints and ultimately elucidate molecular targets important for disease treatment.

Publications:

Darienne R. Myers, Tannia Lau, Evan Markegard, Hyung W. Lim ,Herbert Kasler, Minghua Zhu, Andrea Barczak, John P. Huizar, Julie Zikherman ,David J. Erle , Weiguo Zhang , Eric Verdin, and Jeroen P. Roose. Tonic Signals Through the T cell Adapter Linker for Activation of T Cells Tune Epigenetic Control of Helper T Cell Differentiation. Manuscript in preparation.

Andre Limnander, Julie Zikherman, Tannia Lau, Michael Leitges, Art Weiss, and Jeroen P. Roose, “PKC delta promotes transitional B cell negative selection and limits proximal BCR signaling to enforce tolerance,” Molecular and Cellular Biology, April 2014 34:8 1379; doi:10.1128/MCB.00263-14

Angus L. Dawe, Wayne A. Van Voorhies, Tannia A. Lau, Alexander V. Ulanov, and Zhong Li,“Major impacts on the primary metabolism of the plant pathogen Cryphonectria parasitica by the virulence-attenuating virus CHV1-EP713,” Microbiology, first published on July 9, 2009 as doi: 10.1099/mic.0.029033-0

Presentations:

Cytological Profiling: Imaged Based Classification of Small Molecules. Tannia Lau, Walter Bray, Scott Lokey Ph.D. University of California, Santa Cruz. Chemistry and Program of Biomedical Science and Engineering Retreat to faculty and peers, 2016. Poster Presentation.

Cytological Profiling: Imaged Based Classification of Small Molecules. Tannia Lau, Walter Bray, Scott Lokey Ph.D. Bethesda, MD. NIH Centers for Advancing Research on Botanicals & Other Natural Products (CARBON) program, 2016. Poster Presentation.

Tonic Signals Through the T Cell Adapter LAT Tune Epigenetic Control of Helper T Cell Differentiation. Tannia Lau and Jeroen Roose Ph.D. Asilomar, CA. UCSF/UCB Immunology Retreat to faculty and peers, 2014. Poster Presentation.

Determining the Functional Importance of the CD Loop in the Csk-SH2 Domain. Tannia Lau, Sulyman Barkho, and Patricia Jennings Ph.D. University of California, San Diego. STARTS, 2009. Oral Presentation. 

Awards:

2015- Present, Initiative for Maximizing Student Development (IMSD) Fellowship, UCSC

2015- Present, Navajo Tribal Scholarship

2015, Honorable Mention Recipient for the NSF Graduate Research Fellowship Program (GRFP)

2006 -2010, Navajo Tribal Scholarship

2006- 2009, Scholar, Minority Biomedical Research Support- Research Initiative for Scientific Enhancement (MBRS-RISE)

2008, Annual Biomedical Research Conference for Minority Students (ABRCMS) National Conference Travel and Lodging Scholarship

2008, Society for Advancement of Chicanos and Native Americans in Science (SACNAS) National Conference Travel and Lodging Scholarship

2008, National Institute of Health, Intramural National Institute of Allergy and Infectious Diseases (NIAID) Research Opportunity (INRO) Training Program 

2007-2008, The National Science & Mathematics Access to Retain Talent (SMART) Grant 



 

Adriana Lopez

Research Lab: Melissa Jurica

Department: Molecular, Cell & Developmental Biology

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Francisco Mendez

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Donna Poscablo

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Angel Resendez

Lab Group: Bakthan Singaram

Department: Chemistry and Biochemistry

Research Description: Development of chemical assays and diagnostic tools, biosensors, chemosensors, and boron based synthetic methodology. My current research focuses on the development of a two-component platform for high-throughput analysis of saccharide/sugar biomarkers in urin for gut permeability assessment.

Publications:

Resendez, A.; Halim, A. Md.; Landhage, C.; Hellstrom, M.; Singaram, B.; Webb D.L.; RAPID SMALL INTESTINAL PERMEABILITY ASSAY BASED ON RIBOFLAVIN AND LACTULOSE DETECT BY BIS-BORONIC ACID APPENDED BENZYL VIOLOGENS. Clin. Chim. Acta 2014, In Press

de Boer-Maggard, T. R.; Resendez, A.; Mascharak, P.K., CONSTRUCTION OF A BIOMIMETIC PEROXYNITRITE-GENERATING PLATFORM: A TWO-COMPONENT SYSTEM TO SYNTHESIZE PEROXYNITRITE IN SITU UNDER THE CONTROL OF LIGHT.Chembiochem 2013, 14, 2106.

Saavedra, J. Z.; Resendez, A.; Rovira, A.; Eagon, S.; Haddenham, D.; Singaram, B. REACTION OF InCl3 WITH VARIOUS REDUCING AGENTS: InCl3-NaBH4 MEDIATED REDUCTION OF AROMATIC AND ALIPHATIC NITRUILES TO PRIMARY AMINES. J. Org. Chem. 2012, 77,221-228

Presentations:

INDIUM MEDIATED REDUCTIONS OF AROMATIC AND ALIPHATOC NITRILES TO PRIMARY AMINES. Angel Resendez, Jaime Saavedra, Bakthan Singaram. Society for the Advancement of Chicanos/Latinos and Native Americans in Science (SACNAS) National Conference, San Jose, CA. October 27-30, 2011. Oral Presentation.

REDUCTION OF NITRILES TO PRIMARY AMINES USING InCl3-NaBH4 IN TETRAHYDROFURAN. Angel Resendez, Bakthan Singaram, Jaime Saavedra. University of California-Santa Cruz. Society for the Advancement of Chicanos/Latinos and Native Americans in Science (SACNAS) National Conference, Anaheim, CA. September 29-October 3, 2010. Poster Presentation.

REDUCTION OF NITRILES TO PRIMARY AMINES USING InCl3-NaBH4 IN TETRAHYDROFURAN. Angel Resendez, Bakthan Singaram, Jaime Saavedra. University of California-Santa Cruz, Undergraduate Research Poster Symposium. June 4, 2010. Poster Presentation.

Awards:

UCSC Department of Chemistry Douglas Wren Award Recipient, May 2014

The Louis Stokes Alliance Bridge to Doctorate graduate research fellowship, September 1, 2011-August 30, 2013

The American Chemical Society (ACS) Award for outstanding research oral presentation. Society for the Advancement of Chicanos/Latinos and Native Americans in Science (SACNAS) National conference, San Jose, CA October 29, 2011

Joseph F. Bunnett Undergraduate Research Award. University of California Santa Cruz, May 6, 2011

Minority Access to Research Careers (MARC) Fellowship, University of California Santa Cruz, 2009-2011

 


 

Stefany Rubio

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Cameron Soulette

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copyright of University of California 2011