Caree Carson

IMSD. Class of 2015.

Lab Group: Melissa Jurica

Major: Molecular, Cell, and Developmental Biology

ResearchPurification of the enzyme reverse transcriptase to use in RNA structure mapping of the spliceosome.

Internships/ Presentations/ Awards:

Purification of Reverese Transcriptase. Caree Carson and Melissa Jurica. 5th Annual Summer Research Symposium. UC Santa Cruz. Santa Cruz, CA. Summer 2014. Poster Presentation.

Role of Spt5 Contact Sites in RNA Polymerase II Transcription Activity. Caree Carson and Wisdom Cole with Professor Grant Hartzog in the Summer Research Institute. University of California-Santa Cruz, Summer Research Symposium, 2013. Poster Presentation

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Summer Research Experience 2014, UC Santa Cruz, Summer 2014

Summer Research Institute 2013, UC Santa Cruz, Summer 2013


Eric Curiel

RMI Scholar - 5th Year; Transfer Student from College of the Sequoias

Lab Group: Professor Grant Pogson Lab 

Major: Ecology & Evolutionary Biology

Research: 

Internships/ Presentations/ Awards:

Diversity and Evolution of Innate Immunity Genes in Sea Urchins. Eric Curiel and Grant Pogson. University of California-Santa Cruz, Summer Research Symposium, 2013.

Summer Research Experience, UC Santa Cruz, Summer 2013

Summer Research Experience, UC Santa Cruz, Summer 2012

Indentifying Stem Cell Lines by Morphology and Gene Expression. Eric Curiel, Oscar Fernandez, Amy Ralston. UC Santa Cruz, Undergraduate Summer Symposium. Santa Cruz, CA 95064. August, 12 2011.

MARC/IMSD/CAMP Summer Reaserach Institute. University of California, Santa Cruz. June 20 - August 12, 2010


Jorge De La Rosa

IMSD- Graduate of 2013

Lab Group: 

Major: MCD Biology 

Research

Internships/ Presentations/ Awards: 

Summer Research Experience, UC Santa Cruz, 2013.


Carlos Alberto Espinosa

IMSD

Lab Group: Barry Bowman

Major: Human Biology

ResearchLocalization of proteases in N. crassa, within a new organelled called Unidentified Fungal Organlle (UFO)

Internships/ Presentations/ Awards:

Are Soluble Proteases in the Unidentified Fungal Organelle (UFO) in N. crassa? Carlos Espinosa, Cecilia Im, Marija Draskovic, Barry Bowman. Undergraduate Summer Research Symposium 2014, University of California, Santa Cruz, August 15th, 2014. Poster Presentation

Expression of CD4 and CD8 in the Strains of Mice. Sindy Ramirez and Carlos Espinosa with Professor Martha Zuniga in the Summer Research Institute. University of California-Santa Cruz, Summer Research Symposium, 2013. Poster Presentation

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Summer Research Experience 2014, UC Santa Cruz, Summer 2014

Summer Research Institute 2013, UC Santa Cruz, Summer 2013


Kendy Hoang

IMSD. Class of 2015.

Lab Group: 

Major: Biomolecular Engineering/Molecular, Cell, and Developmental Biology

Research

Internships/ Presentations/ Awards:

Cloning of SPT5 Fragment using Molecular Cloning Techniques. Kendy Hoang and Joanna Perez with Professor Grant Hartzog in the Summer Research Institute. University of California-Santa Cruz, Summer Research Symposium, 2014. Poster Presentation

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Summer Research Institute 2014, UC Santa Cruz, Summer 2014


Sharon Idiga

IMSD. Class of 2015.

Lab Group: Professor Pradip Mascharak Lab

Major: Molecular, Cell, and Developmental Biology

ResearchPeroxynitrite (PN) is a reactive nitrating and oxidative species that plays a key role in inflammation-mediated disease states, from neurodegenerative disorders to diabetes. PN is formed in the radical terminating reaction between nitric oxide (NO) and superoxide. It has been difficult to observe PN directly within cells due to its transient nature. With a photo-controlled peroxynitrite-generating platform, the Mascharak lab has developed a system that is able to release PN in situ, to better understand the dynamic chemistry of PN. Stable metal nitrosyl, [Mn(PaPy3)(NO)]ClO4 (PaPy3=N,N-bis-(2-pyridylmethyl)amine-N-ethyl-2-pyridine-2-carboxamide), was used as the source of NO because it rapidly releases NO upon illumination with visible light. To match the rapid release of NO from the nitrosyl, the xanthine oxidase/hypoxanthine (XO/HX) system was employed as the source of superoxide. Both sources were encapsulated in a sol-gel matrix to avoid contamination. A multi-well plate was used to study the chemistry of the precursors as well as PN. Construction of the PN-generating platform was completed by layering both NO and XO sol-gels at the bottom of individual wells. Release of the precursor molecules is triggered with exposure to low powered visible light and the addition of HX. This light-activated platform allows the study of PN-mediated chemistry under varied flux ratios and pH conditions. We plan to utilize the multi-well platform to study the reactions of PN with various biomolecules such as amino acids, peptides, and lipids.

Publications:

deBoer-Maggard, R. T., Palomino, R. I., Idiga, O. S., Millhauser, L. G., and Mascharak, K. P., Nitration of Tyrosine by Peroxynitrite Generated In Situ in a Light-Controlled Platform: Effects of pH and thiols. Journal of Inorganic Biochemistry. September 2014.

Internships/ Presentations/ Awards:

ENGINEERING A PEROXYNITRITE-GENERATING PLATFORM; Sharon Idiga, Tara deBoer, Pradip Mascharak. 2014 Undergraduate research symposium, UCSC, August 2014. Poster Presentation

HISTIDINE KINASES: A TWO-COMPONENT SIGNAL TRANSDUCTION PATHWAY; Sharon Idiga, Manasi Bhate, William DeGrado. Summer Research Training Program Symposium/Oral Presentation. July 2014. Poster Presentation

ENGINEERING A PEROXYNITRITE-GENERATING PLATFORM; Sharon Idiga, Tara deBoer, Pradip Mascharak. California Alliance for Minority Participation symposium. UC Irvine. Irvine, CA, February 2014. Poster Presentation

Recombinant Protein Purification of mCherry. Sharon Idiga and Rolando Perez with Professor Melissa Jurica in the Summer Research Institute. University of California-Santa Cruz, Summer Research Symposium, 2013. Poster Presentation

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California Alliance for Minority Participation : Special Merit Physical Science/Engineering. California Alliance for Minority Participation Symposium. Irvine, CA. UC Irvine, February 2014

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UCSF Summer Research Training Program, UC San Francisco, 2014.

Summer Research Institute, UC Santa Cruz, 2013.


Frank Leon

RMI Scholar - 5th year; Transfer Student from Saddleback College

Lab Group: Bill Saxton Lab

Major: Molecular, Cell and Developmental Biology

Research:

Internships/ Presentations/ Awards:

Summer Research Experience, UC Santa Cruz, Summer 2013

Research Undergraduate Experience Ohio State University. Summer 2012.


Ramon Martinez

IMSD.

Lab Group: Professor Melissa Jurica

Major: Biochemistry and Molecular Biology

Research:

Internships, Presentations, and Awards:

Preparation of a tRNA Amber Suppressor for Site-Directed Fluorophore Incorporation into Ribosome-Bound nascent Proteins. Ramon Martinez, Arelys Rosado, Silvia Cavagnero, Ph.d. University of Wisconsin-Madison. University of California-Santa Cruz, 5th Annual Summer Research Symposium. Santa Cruz, CA. August 15th, 2014. Poster Presentation.

Expression of Human SF3B Complex by Wheat Germ in vitro Synthesis. Ramon Martinez, Beth Prichard, Yaeta Endo, and Melissa Jurica. 2013 ABRCMS National Conference, Nashville, TN., November 2013. Poster Presentation.

Expression of Human SF3B Complex by Wheat Germ in vitro Synthesis. Ramon Martinez, Beth Prichard, Yaeta Endo, and Melissa Jurica. University of California-Santa Cruz, Summer Research Symposium, 2013. Poster Presentation
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Summer Research Experience. UC Santa Cruz, Summer 2013 

Undergraduate Research Institute and Symposium.  Summer 2012

Gerardo Perez

RMI Scholar - 5th Year; Transfer Student from Hartnell College

Lab Group: Professor Phil Berman                                      

Major: Biomolecular Engineering

Research:The focus of my project is investigating genetic connectivity of populations of coronet fish (Fistularia commersoni) on a global scale.  We're interested in determining the amount of larval exchange occurring between populations as well as determining the spatial scale at which groups of individuals are genetically differentiated.  To address these interests I will be sequencing the mitochondrial marker cytochrome oxidase I and investigating nucleotide changes that have accumulated in groups of coronet fish over time.

 Internships/ Presentations/ Awards:

Prime-Boost with Cell Surface Expressed Clinical Isolates of HIV Env. Gerardo Perez, Javier Morales, Sara M. O'Rourke, Phillip W. Berman. University of California-Santa Cruz, Summer Research Symposium, 2013.

Summer Research Experience, UC Santa Cruz, Summer 2013

ACCESS Summer Research Institute. University of California, Santa Cruz. June 13–August 12, 2011

Synthesis of vibrio cholerae biofilm inhibitors. Gerardo Perez, Brian León, Roger G. Linington. The University of California of Santa Cruz, Santa Cruz CA. 2011 Undergraduate Summer Research Symposium.  Aug. 12. 2011. University of California, Santa Cruz. Santa Cruz. Poster Presentation


Sindy Ramirez

IMSD. Class of 2015.

Lab Group: Dr. Karen Ottemann

Major: Human Biology

Research:

Internships/ Presentations/ Awards:

Mutagenesis of Helicobacter Pylori's Chemoreceptor TLPD in Conserved CZB Domain. Sindy Ramirez, Kieran Collins and Dr. Karen Ottemann. 5th Annual Summer Research Symposium. University of California-Santa Cruz. Santa Cruz, CA. August 15th, 2014. Poster Presentation.

TLPD Living in the Fast Lane. Sindy Ramirez and Karen Ottemann. 2014 Cailfornia Alliance for Minority Participation Statewide Undergraduate Research Symposium. Irvine, CA. February 2014. Poster Presentation.

Expression of CD4 and CD8 in the Strains of Mice. Sindy Ramirez and Carlos Espinosa with Professor Martha Zuniga in the Summer Research Institute. University of California-Santa Cruz, Summer Research Symposium, 2013. Poster Presentation

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Summer Research Experience 2014, UC Santa Cruz, Summer 2014

Summer Research Institute 2014, UC Santa Cruz, Summer 2013


Sirena Sechslingoff

IMSD- Graduate of 2013

Lab Group: Professor Ottemann

Major: Molecular Cell and Developmental Biology

Research

Internships/ Presentations/ Awards:


Ruth Zuniga

IMSD. Class of 2015.

Lab Group: Bakthan Singaram

Major: Chemistry

Research:

Internships/ Presentations/ Awards:

Pursuit of Selectivity and Sensitivity for Saccharide Recognition by a Two-Component Boronic Acid-Based Fluorescent System. Ruth Zuniga, Angel Resendez, and Bakthan Singaram. 5th Annual Summer Reseasrch Symposium. University of California-Santa Cruz. August 15th, 2014. Poster Presentation

Determination of Iron Concentration Using Calorimetric Analysis. Rene Mercado and Ruth Zuniga with Professor Pradip Mascharak in the Summer Research Institute. University of California-Santa Cruz, Summer Research Symposium, 2013. Poster Presentation

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IMSD Summer Research Institute, UC Santa Cruz, Summer 2013


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