Giselle Aguayo

IMSD- Senior

Lab Group: Fitnat Yildez 

Major: Biochemistry & Molecular Biology 

Research: 

Identification genes and transcriptional regulators that confer resistance to the cAMP antibiotic Polymyxin B in V. cholerae.  

Internships/Presentations/Awards:

Summer Research Experience 2018, University of California, Santa Cruz. Santa Cruz, CA. Summer 2018

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Identification of  Transcriptional Regulators of CarRS two-component Signalling System in Vibrio cholerae. Giselle Aguayo, Kyle A. Floyd, Ana L. Gallego-Hernandez, Fitnat Yildiz*, Microbiology and Environmental Toxicology, University of California, Santa Cruz, 9th Annual Physical and Biological Summer Research Symposium, 2018. Poster Presentation 

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Rachel Barocio

IMSD Junior

Lab Group: Hartzog Lab

Major: Molecular, Cell, and Developmental Biology

Research: 

Spt5 is the only transcription regulatory factor conserved across all domains of life. It is an essential regulator of RNA Polymerase II and is thought to assist in elongation past nucleosomes, enhancing processivity. I am contributing to several ongoing projects investigating the structural domains of Spt5 and genetic analysis of spt5Cs-, a cold sensitive mutant.

Internships/Presentations/Awards:

Harvard University, Systems Biology Internship, 2018
Engineered microbes are increasingly being used to manufacture pharmaceuticals, nutrients, and biofuels. To make use of transgenic microbes outside of a secure laboratory environment, their growth must be biologically and physically contained to prevent colonization of unintended environments. I aided in engineering a kill switch that responds to environmental pH in bacteria. Engineering native members of the human microbiome allows us to make use of them for diagnosing and treating disease in the gut.

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"Engineered Kill Switches for Containment of Transgenic Microbes"
Finn Sterling, Pamela Silver, Bioengineering, Harvard Medical School, Annual Biomedical Research Conference for Minority Students, 2018. Poster Presentation.

"Synthetic Gene Circuits for Bio-containment of E. coli"
Finn Sterling, Pamela Silver, Harvard University, Summer Village Research Poster Session, 2018. Poster Presentation.

"Synthetic Gene Circuits for Bio-containment of E. coli"
Finn Sterling, Pamela Silver, Harvard Medical School, Department of Systems Biology, 2018. Poster Presentation.

"Design of Evolutionarily Stable Kill Switches"
Finn Sterling, Pamela Silver, University of California, Santa Cruz, 9th Annual Physical and Biological Research Symposium, 2018. Poster Presentation.
Travel Scholarship, Society for Advancement of Chicanos and Native Americans in Science, 2018.
 

Alejandro Cabrera-Cortez

IMSD Fellow

Lab Group: 

Lokey Lab Group

Major: Biochemistry & Molecular Biology 

Research: 

Internships/Presentations/Awards:

Summer Research Institution 2018, University of California, Santa Cruz. Santa Cruz, CA. Summer 2018

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Mutagenesis of RPB7 to Examine the Rpb7 and Spt5 Interactions with RNA Polymerase II in S. cerevisiae. Alejandro Cabrera-Cortez1, Sabrina Inez Pedrosa2, Grant Hartzog*, Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, 9th Annual Physical and Biological Summer Research Symposium, 2018. Poster Presentation

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Musette Caldera 

IMSD-Senior

Lab Group: Lindsay Hinck 

Major: Biochemistry and Molecular Biology

Research: 

Internships/Presentations/Awards:   

Summer Research Experience 2018, University of California, Santa Cruz. Santa Cruz, CA. Summer 2018                                                                            

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Lactation in Robo1+/+ and Robo-/- Mice. Musette Caldera, Oscar Cazares, Lindsay Hinck*, Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, 9th Annual Physical and Biological Summer Research Symposium, 2018. Poster Presentation                                                                              

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Kevin Chen

IMSD Senior

Lab Group: Hinrich Boeger 

Major: Molecular, Cell, and Developmental Biology & Mathematics 

Research: 

Activator function has long term effects on chromatin. 

Internships/Presentations/Awards:

Summer Research Experience 2018, University of California, Santa Cruz. Santa Cruz, CA. Summer 2018

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 ChEC-CLK it out! Analyzing Extent of Kinetic Memory in Activator Pho4 Binding. Kevin Chen, Robert Shelansky, Hinrich Boeger*, Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, 9th Annual Physical and Biological Summer Research Symposium, 2018. Poster Presentation 
 
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Imon Islam  

IMSD Senior

Lab Group: Chistopher Vollmer

Major: Biochemistry & Molecular Biology 

Research: 

Using the power of molecular biology tips and tricks, we can turn any low accuracy long read sequencer into a highly accurate and efficient sequencer. 

Internships/Presentations/Awards:

Summer Research Insititute 2017, University of California Santa Cruz. Santa Cruz, CA. Summer 2017

Summer Research Experience 2018, University of California, Santa Cruz. Santa Cruz, CA. Summer 2018

Big Data 2 Knowledge (BD2K) 2018

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Assessing Applicability of New Long Read Low Error Method (R2C2) on Metagenomic Samples. Imon Islam, Ruby Torres, Charles Cole, Christopher Vollmers*, Biomolecular Engineering, University of California, Santa Cruz, 9th Annual Physical and Biological Summer Research Symposium, 2018. Poster Presentation

Crystallization & X-ray Diffraction of Proteinase K: A Tool for Alzheimer's Plaque. Liseth Iniguez, Imon Islam, and Carrie Partch, Chemistry and Biochemistry, University of California, Santa Cruz, 8th Annual Physical and Biological Sciences Summer Research Symposium, 2017. Poster Presentation.  

UCSC Summer Undergraduate Poster Symposium August 2017                                                  Presented a project on "Protein K Crystallography as a tool for investigating Alzheimer’s." 

UCSC Summer Undergraduate Poster Symposium August 2018                                                  Presented a project on "Assessing Applicability of New Long Read Low Error Method (R2C2) on Metagenomic Samples."

Emory Laney Graduate School STEM Symposium October 2018                                                  Presented a project on "Assessing Applicability of New Long Read Low Error Method (R2C2) on Metagenomic Samples." 

First Place for Poster Presentations*

SACNAS Conference Presentation September 2018                                                                       Presented a project on "Assessing Applicability of New Long Read Low Error Method (R2C2) on Metagenomic Samples."

ABRCMS Conference Poster Acceptance September 2018                                                            Northern California Computational Biology Symposium October 2018                                         Presented a project on "Assessing Applicability of New Long Read Low Error Method (R2C2) on Metagenomic Samples."

SACNAS Conference Attendee 2017-2018                                                                                                  ****************************************************************************** 

United Way of Greater Los Angeles Scholarship 2014     

Models of Excellence Scholarship 2015                   

Models of Excellence Scholarship 2017

Pudan-Dimao Scholarship 2018

Models of Excellence Scholarship 2018

Emory Laney Graduate School STEM Symposium Travel Scholarship 2018

Cheyenne Jarman

IMSD Senior

Lab Group: Mark Carr

Major: Computer Science & Marine Biology

Research:  My research focuses on the impact of meso-predators within a kelp forest ecosystem.

Internships/Presentations/Awards:

 Summer Research Experience 2018, University of California, Santa Cruz. Santa Cruz, CA. Summer 2018

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A Quantitative Approach to Urchin Gut Content Analysis. Cheyenne N. Jarman,Joshua G. Smith, Mark H. Carr*, Ecology and Evolutionary Biology, University of California, Santa Cruz, 9th Annual Physical and Biological Summer Research Symposium, 2018. Poster Presentation 

A Visual Approach to Sea Urchin Diet Characterization. Cheyenne N. Jarman, Joshua G. Smith, Mark H. Carr, Ecology and Evolutionary Biology, University of California, Santa Cruz, Western Society of Naturalists, 2018. Poster Presentation

Visualizing Kelp Forest Species Interactions. Cheyenne N. Jarman, Joshua G. Smith, Mark H. Carr, Ecology and Evolutionary Biology, University of California, Santa Cruz, Broadening Participation in Visualization, 2018. Poster Presentation

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Koret Scholar (2018)

Women Diver Hall of Fame – Ella Jean Morgan Memorial Dive Training Grant (2018)


Deborah Leopo

IMSD Senior

Lab Group: Jonathan Zehr

Major: Marine Biology

Research:  

Internships/Presentations/Awards:

 

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Amy Leslie

IMSD Senior 

Lab Group: Alan Zahler 

Major: Biochemistry and Molecular Biology 

Research: 


Internships/Presentations/Awards:

 

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Patricia Mendez

IMSD Senior 

Lab Group: Jurica Lab

Major: Biochemistry and Molecular Biology 

Research: 


Internships/Presentations/Awards:

 

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Aldrex Munsayac

IMSD Junior

Lab Group: Stone Lab  

Major: Chemistry

Research: 

Understanding telomere biology using single-molecule biophysics

Internships/Presentations/Awards:

Summer Research Institute 2018, University of California Santa Cruz. Santa Cruz, CA. Summer 2018

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 Understanding the structural differences in DNA. Aldrex Munsayac, Catherine Rosales, and Michael D. Stone, Chemistry and Biochemistry, University of California, Santa Cruz, 9th Annual Physical and Biological Science Summer Research Symposium, 2018. Poster Presentation.
 
 
 
 
 

Esther Muñoz 

IMSD Senior  

Lab Group: Chad Saltikov

Major: Earth Sciences, Planetary Sciences Concentration

Research: 

The biogeochemical cycling of arsenic 

Internships/Presentations/Awards:

NASA AMES Research Center [2014]: 
Characterization of Forward Osmosis Membrane for Wastewater Reclamation Applications
Presented Research at NASA AMES Base and City College of San Francisco (CCSF)

SFSU (NIH Bridges too Baccalaureate) [2015]: 
Capability of Top-Brand Sunscreens vs. Natural African Shea Butter Against UV-Radiation on UV-Sensitive E. coli
Effects of Fluoride Exposure on Zebrafish Embryos
Presented Research at SFSU and CCSF

SFSU (NIH Bridges) [2016]: 
Identifying the Gene Responsible for Changing Hydroxylamine to Nitrite in Ammonia- Oxidizing Archaea
Presented Research at SFSU, CCSF and SACNAS (2018)

Summer Research Experience 2018, University of California, Santa Cruz. Santa Cruz, CA. Summer 2018 

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Arsenic Biogeochemical Cycling Under Extreme, Archean-like Conditions. Esther C. Munoz, Sanjin Mehic, Chad Saltikov*, Microbiology and Environmental Toxicology, University of California, Santa Cruz, 9th Annual Physical and Biological Summer Research Symposium, 2018. Poster Presentation 

Presented at NASA & City College of San Francisco (CCSF) 

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Undergraduate Research Scholarship (UCSC) 

James Court-Earth Science Department Award (CCSF) 

Koret Foundation Award (CCSF) 

Ruth K. Deb Endowment Award (CCSF) 

Bernard Osher Foundation Award (CCSF)

Osher Initiative Award (CCSF) 

NSF Scholarship (CCSF) 

Bridges to Baccalaureate Program-NIH (CCSF) 

Pan-American Roundtable Award (CCSF)  

Physical Science Dept Award (David Doshay and Aviva Garrett) (2018)
IMSD (2018) 

Hochebori Ouattara 

IMSD Senior

Lab Group: Pradip Mascharak

Major: Biochemistry & Molecular Biology 

Research: 

Working on Gold material and how it can affect or treat tuberculosis. 

Internships/Presentations/Awards:

Summer Research Experience 2017, University of California Santa Cruz. Santa Cruz, CA. Summer 2017 
 
Summer Research Experience 2018, University of California Santa Cruz. Santa Cruz, CA. Summer 2018 

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Cationic Au(I) Complexes and their Antibacterial Effects. Hochebori Ouattara, Jenny Stenger-Smith, Pradip Mascharak*, Chemistry and Biochemistry, University of California, Santa Cruz, 9th Annual Physical and Biological Summer Research Symposium, 2018. Poster Presentation 

Structural Requirements for Broadly Protecting Antibodies to the Respiratory Syncytial Virus G Protein. Hochebori Ouattara, Stas Fedechki, Natasha George, Joshua Dillen, and Rebecca M. Dubois, Biomolecular Engineering University of California, Santa Cruz, 8th Annual Physical and Biological Sciences Summer Research Symposium, 2017. Poster Presentation

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ACS scholar   

Joseph Palacios

IMSD Senior

Lab Group: 

Partch Lab

Major: General Biology

Research: 

Circadian clock in cyanobacteria

Internships/Presentations/Awards:

Summer Research Institute 2018, University of California Santa Cruz. Santa Cruz, CA. Summer 2018 

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Optimizing Crystal Screens of Proteinase K and Limited Proteolysis on PER2. Joseph G. Palacios1, Lauren Yee1, Carrie Partch*, Chemistry and Biochemistry, University of California Santa Cruz, 9th Annual Physical and Biological Summer Research Symposium, 2018. Poster Presentation 

Andrea Ramirez 

IMSD Scholar-Senior 

Lab Group: Alan Zahler

Major: Molecular, Cell, & Developmental Biology 

Research: 

The Zahler Lab looks at a mechanism known as alternative splicing and how it is regulated, particularly by cis and trans elements. We exploit powerful genetic, molecular biology, and bioinformatics tools of a worm species, C. elegans, to do so. 

Presentations/Awards/Internships:

Summer Research Insistution 2017, University of California-Santa Cruz, Santa Cruz, CA. Summer 2017

Summer Research Experience 2018, University of California-Santa Cruz, Santa Cruz, CA. Summer 2018

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740 Loop Tolerations of Spliceosomal Component PRP-8. Andrea Ramirez and Alan Zahler*, Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, 9th Annual Physical and Biological Summer Research Symposium, 2018. Poster Presentation 

Expressing HIS5 in Yeast Through Exon Skipping. Andrea Ramirez, Kennedy Allen, and Grant Hartzog, Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, 8th Annual Physical and Biological Science Summer Research Symposium, 2017. Poster Presentation

PRP8 Alleles Suppress Cryptic Splicing in C. elegans. Andrea Ramirez 21st Annual Undergraduate Research Symposium. June 2018.   


Lucia Rivas 

IMSD Senior 

Lab Group: Lindsay Hinck

Major: Neuroscience 

Research: 

Internships/Presentations/Awards:

Summer Research Insititute 2017, University of California Santa Cruz. Santa Cruz, CA. Summer 2017 

Summer Research Experience 2018, University of California-Santa Cruz, Santa Cruz, CA. Summer 2018

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Role of Vangl-like 2 and BMI1 in Normal and Breast Cancer Development. Lucia Rivas, Stefany Rubio, Lindsay Hinck*, Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, 9th Annual Physical and Biological Summer Research Symposium, 2018. Poster Presentation 

Identifying Wolbachia in Drosophila melanogaster and Local Insects through PCR and Fluorescent Microscopy. Lucy Rivas, Julia Martin, Shelbi Russell, and William Sullivan, Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, 8th Annual Physical and Biological Science Summer Research Symposium, 2017. Poster Presentation


Mirella Rivera-Velasquez

IMSD Junior

Lab Group:

Major: Neuroscience

Research:  

Internships/Presentations/Awards:

Summer Research Insistution 2018, University of California-Santa Cruz, Santa Cruz, CA. Summer 2018

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Evidence that Autoreactive Thymocytes Bearing High-Affinity TCRs Can Escape Negative Selection by Down-Regulating CD8 and CD4. Mirella Rivera-Velasquez2, Eimy Castellanos1, Yitzhar Goretsky, Alicia Freedman, Martha Zúñiga*, Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, 9th Annual Physical and Biological Summer Research Symposium, 2018. Poster Presentation 

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Catherine Rosales

IMSD Senior 

Lab Group: 

Major: Molecular, Cell, and Developmental Biology 

Research: 


Internships/Presentations/Awards:

 

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Jennie Ruelas Castillo 

IMSD Junior

Lab Group: William Sullivan 

Major: Molecular, Cell, & Developmental Biology 

Research: 

The focus of my research is to gain an understanding of how Wolbachia interacts with host germline development to ensure that the bacteria are transmitted to the next generation of hosts. Specifically, I am investigating how this bacterium is able to rescue the loss of the gene meiotic P26 (mei-P26),a ubiquitin ligase protein that is necessary for oocyte cell differentiation and the regeneration of germ cells. 

Internships/Presentations/Awards:

Summer Research Insititute 2017, University of California Santa Cruz. Santa Cruz, CA. Summer 2017 
Summer Research Experience 2018, University of California Santa Cruz. Santa Cruz, CA. Summer 2018

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Inhibition of the Metalloenzyme, Soybean Lipoxygenase. Jennie Ruelas Castillo, Julieta Gomez, Natalia Ubilla, and Theodore Holman, Chemistry and Biochemistry, University of California, Santa Cruz, 8th Annual Physical and Biological Science Summer Research Symposium, 2017. Poster Presentation

Wolbachia restores normal oogenesis in Drosophila hosts lacking factors for germ cell maintenance and differentiation. Jennie Ruelas. Hartnell College, STEM Internship 2018. 

Wolbachia restores normal oogenesis in Drosophila hosts lacking factors for germ cell maintenance and differentiation. Jennie Ruelas.  Salem, Massachusetts, Wolbachia Conference 2018.

Wolbachia restores normal oogenesis in Drosophila hosts lacking factors for germ cell maintenance and differentiation. Jennie Ruelas. University of California, Santa Cruz, 9th Annual Physical and Biological Science Summer Research Symposium, 2018. 

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Dean’s Honors Fall  2017, Winter 2018, Spring 2018. 

1st Place Poster Presentation Award  Wolbachia Conference 2018 

Wolbachia Travel Scholarship 


Diana Sernas  

IMSD Junior  

Lab Group: Grant Hartzog

Major: Pure Mathematics 

Research: 

To identify Wolbachia genes altering host DNA packaging, we are introducing a library of individually synthesized and codon-optimized Wolbachia genes into budding yeast. Following with screens for defects associated with altered transcription or chromatin disruption. Chromatin components and transcriptional regulators are conserved across eukaryotes, we propose that Wolbachia proteins altering gene expression in host cells will similarly interfere with these processes when expressed in yeast.

Internships/Presentations/Awards:

Summer Research Experience 2017, University of California Santa Cruz. Santa Cruz, CA. Summer 2017 

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Juicy details of Hi-C. Diana Sernas, Keith Fraga, Javier Arsuaga*, Mathematics & Molecular and Cellular Biology, University of California, Davis. 9th Annual Physical and Biological Summer Research Symposium, 2018. Poster Presentation

Identifying Wolbachia Effectors in S. Cerevisiaeby Affecting Ty Expression. Diana Sernas, Jennifer Liu, Michael Doody, and Grant Hartzog, Molecular, Cell and Developmental Biology, University of California, Santa Cruz, 8th Annual Physical and Biological Science Summer Research Symposium, 2017. Poster Presentation. 


SACNAS: National Diversity in STEM Conference October 2018
Poster Presentation San Antonio, TX
Identifying Wolbachia Effectors in S. Cerevisiae by Affecting Ty Expression

9th Annual Physical and Biological Science Summer Research Symposium August 2018
Poster Presentation Santa Cruz, CA
Juicy Details of Hi-C

Infinite Possibilities Conference: National Math Conference April 2018
Poster Presentation Washington, D.C.
Identifying Wolbachia Effectors in S. Cerevisiae by Affecting Ty Expression

CAMP: Statewide Research Symposium Februrary 2018
Poster Presentation Irvine, CA
Identifying Wolbachia Effectors in S. Cerevisiae by Affecting Ty Expression

8th Annual Physical and Biological Science Summer Research Symposium August 2017
Poster Presentation Santa Cruz, CA
Identifying Wolbachia Effectors in S. Cerevisiae by Affecting Ty Expression

 
 
 

Joanna Tran 

IMSD Senior

Lab Group: Ingrid Parker 

Major: Plant Science & Molecular Biology 

Research: 

Internships/Presentations/Awards: 

Summer Research Insititute 2017, University of California Santa Cruz. Santa Cruz, CA. Summer 2017 

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Tolerance of Salt Marsh Natives to Abiotic Stressors: a Tool to Improve Restoration. Joanna Tran, Karen Tanner, Ingrid Parker*, Ecology and Evolutionary Biology, University of California, Santa Cruz, 9th Annual Physical and Biological Summer Research Symposium, 2018. Poster Presentation

Engineering a reporter gene to select for splicing mutations in S. cerevisiae. Joanna Tran, Jessica Jones, Beckett Whittier, and Melissa Jurica, Molecular, Cell, and Developmental Biology University of California, Santa Cruz, 8th Annual Physical and Biological Sciences Summer Research Symposium, 2017. Poster Presentation

Natalia Ubilla  

IMSD Senior 

Lab Group: Glenn Millhauser

Major: Biochemistry & Molecular Biology 

Research: 

Prion diseases are fatal, neurodegenerative diseases that affect mammals. Chronic Wasting Disease, Mad-Cow Disease, and scrapie are caused by the misfolded prion protein (PrP). The infectious isoform refolds healthy PrP on the surface of brain cells, furthering the development of prion pathogenesis. In prion diseases, the N-terminus is thought to be overactive, permanently holding open ion channels and allowing for unchecked ion flux, leading to cell death. The C-terminus has a regulatory role in which copper-binding promotes a cis interaction between the C and N termini of the PrP. Given that the glycosylation sites are included in the copper binding region, we are investigating the structural consequence of the glycans on the cis interaction. My project consist of 1) engineering PrP to have para-acetylphenylalanine, a reactive unnatural amino acid at its two glycosylation sites 2) synthesizing aminooxy N-acetylglucosamine, a reactive sugar starting from N-acetylglucosamine in a phase transfer reaction followed by a hydrazine reduction 3) coupling the glycans to the unnatural amino acids followed by extension using glycosyltransferase to generate our glycoprotein. Using HSQC NMR, we will determine whether or not the glycans are assisting the C terminus in regulating the N terminus through the cis interaction.  

Internships/Presentations/Awards:

Summer Research Insititute 2017, University of California Santa Cruz. Santa Cruz, CA. Summer 2017 
 
Summer Research Experince 2018, University of California Santa Cruz. Santa Cruz, CA. Summer 2018 
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The Role of Glycosylation on the cisInteraction between the C and N Termini of the Prion Protein. Natalia Ubilla, Kevin Schilling, Glenn Millhauser*, Chemistry and Biochemistry, University of California, Santa Cruz, 9th Annual Physical and Biological Summer Research Symposium, 2018. Poster Presentation 

Inhibition of the Metalloenzyme, Soybean Lipoxygenase. Natalia Ubilla, Julieta Gomez, Jennie Ruelas Castillo, and Theodore Holman, Chemistry and Biochemistry, University of California, Santa Cruz, 8th Annual Physical and Biological Science Summer Research Symposium, 2017. Poster Presentation

The role of glycosylation on the cis interaction between the C and N termini of the prion protein. Natalia Ubilla. SACNAS Conference, San Antonio, Texas October 2018 

The role of glycosylation on the cis interaction between the C and N termini of the prion protein. Natalia Ubilla. Alias Campus, Hartnell College, Salinas, July 2018   

The role of glycosylation on the cis interaction between the C and N termini of the prion protein. Natalia Ubilla. Division of Physical and Biological Sciences Jack Baskin School of Engineering 21st Annual Undergraduate Research Poster Symposium, University of California, Santa Cruz, June 2018 

The role of glycosylation on the cis interaction between the C and N termini of the prion protein. Natalia Ubilla. Koret Research Slam, University of California, Santa Cruz, June 2018 

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Koret Undergraduate Research Scholarship - 2017

Dean’s Honor - Spring 2016  

Dean's Honor - Fall 2018

Tonk Fink Memorial Student Award, 2018


Lauren Yee

IMSD Senior

Lab Group: Carrie Partch

Major: Molecular, Cell and Developmental Biology 

Research: 

Internships/Presentations/Awards: 

Summer Research Insititute 2018, University of California Santa Cruz. Santa Cruz, CA. Summer 2018 

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