I am currently researching the circadian clock of various cell types. My main focus is to study the intrinsic responses of these cell types, and the ways in which microbes, such as Streptococcus pneumoniae, can affect the host’s circadian rhythms.
I am researching 2 amyloid-beta mutants in rescuing the detrimental effects of their wild-type counterpart, using a transgenic Drosophila model. Our aim is to discover a more effective treatment in combating Alzheimer’s Disease.
I am researching the different exogenous and endogenous factors that contribute to the neurodegeneration of Alzheimer’s disease. We’re specifically looking at two missense mutations on the Aꞵ peptide that could reduce its aggregation in vivo in drosophila models.
At the Pourmand Lab, our research centers on creating innovative technologies that advance the fields of biosensors and biotechnology. Our current work includes developing nanopipette-based biosensors for real-time, single-cell detection, as well as disposable biosensors designed for point-of-care diagnostics.
I contribute to research investigating the effects of psychedelics on neuroplasticity, with a focus on 5-HT2AR-expressing neurons to study the neural mechanisms underlying behavioral and synaptic changes.
Investigating HIF gene expression and its relation to circadian rhythm regulation within zebrafish models.
Synthesis of main group metalloporphyrins for use as a tunable Lewis acid catalyst, done in an effort to aid in the sustainability of chemical synthesis when used in place of precious metals used in catalysis today.
My research focuses on creating immiscible Ruthenium Copper alloy nanoparticles with good electrochemical activity for hydrogen evolution reaction (HER) and oxygen evolution reaction (OER).
Investigating and aiming to better understand how MAPK activity regulates chromatin accessibility in ESCs (embryonic stem cells).
Director, STEM Diversity Research Programs Email: yuli@ucsc.edu Office Location: JBE 135
